Hosts- Gene Regulation

Researcher Name: Yurchenko, Vyacheslav

Research Area(s): Computational Biology, Gene Regulation, Genomics and Proteomics, molecular parasitology

Affiliation: University of Ostrava

Country: Czechia

Website 

Scientific Interests:

We are doing molecular parasitology sensu lato with a particular focus on trypanosomatids, a group that unites pathogenic to humans Trypanosoma and Leishmania with one-host parasites of insects. We use the whole arsenal of modern molecular biology and biochemistry techniques to address different scientific questions.

Some of the 2023 publications:

1. Macedo, D.H., Grybchuk, D., Režnarová, J., Votýpka, J., Klocek, D., Yurchenko, T., Ševčík, J., Magri, A., Urda Dolinská, M., Záhonová, K., Lukeš, J., Servienė, E., Jászayová, A., Serva, S., Malysheva, M.N., Frolov, A.O., Yurchenko, V., Kostygov, A.Y. Diversity of RNA viruses in the cosmopolitan monoxenous trypanosomatid Leptomonas pyrrhocoris. BMC Biol., 2023, 21(1): 191. PMID: 37697369. doi:10.1186/s12915-023-01687-y
2. Albanaz, A.T.S., Carrington, M., Frolov, A.O., Ganyukova, A.I., Gerasimov, E.S., Kostygov, A.Y., Lukeš, J., Malysheva, M.N., Votýpka, J., Zakharova, A., Záhonová, K., Zimmer, S.L., Yurchenko, V., Butenko, A. Shining the spotlight on the neglected: new high-quality genome assemblies as a gateway to understanding the evolution of Trypanosomatidae. BMC Genomics, 2023, 24: 471. PMID: 37605127. doi:10.1186/s12864-023-09591-z
3. Zakharova, A., Tashyreva, D., Butenko, A., Morales, J., Saura, A., Svobodová, M., Poschmann, G., Nandipati, S., Zakharova, A., Noyvert, D., Gahura, O., Týč, J., Stühler, K., Kostygov, A.Y., Nowack, E.C.M., Lukeš, J., Yurchenko, V. A neo-functionalized homolog of host transmembrane protein controls localization of bacterial endosymbionts in the trypanosomatid Novymonas esmeraldas. Curr. Biol., 2023, 33(13): 2690-2701. PMID: 37201521. doi:10.1016/j.cub.2023.04.060
4. Kachale, A., Pavlíková, Z., Nenarokova, A., Roithová, A., Durante, I.M., Miletínová, P., Záhonová, K., Nenarokov, S., Votýpka, J., Horáková, E., Ross, R.L., Yurchenko, V., Beznosková, P., Paris, Z., Valášek, L.S., Lukeš, J. Short tRNA anticodon stem and mutant eRF1 allow stop codon reassignment. Nature, 2023, 613(7945): 751-758. (Cover paper). PMID: 36631608. doi:10.1038/s41586-022-05584-2

This offer applies to trainees/researchers eligible for the following fellowships

Everyone (not restricted to fellowship holders)

Contact:

vyacheslav.yurchenko@osu.cz