“Treatment of the metabolic syndrome by siRNA targeting apolipoprotein CIII”
Patricia Recio López did her bachelor in biology and specialized in sanitary biology at Complutense University of Madrid, Spain. After that, she did her master in biomedicine at the same university and performed her master´s thesis “Effects of a dual glucacon-GLP1 receptor agonist in the activation of brown adipose tissue in obese mice” at Biomedical Research Institute “Alberto Sols” in Madrid.
Then, she decided to go abroad to do an ERASMUS + Practices at Karolinska Institutet, Stockholm, Sweden, where she decided to continue her development and started her PhD studies in which she is now studying the role of apolipoprotein CIII in the pathophysiology of diabetes mellitus.
The article has been published in BioFactors, Volume 49, Issue 1, 2023. | Interview with Patricia Recio-López
|Pradeep Manuneedhi Cholan|
“Transplantation of high fat fed mouse microbiota into zebrafish larvae identifies MyD88-dependent acceleration of hyperlipidaemia by Gram-positive cell wall components”
Dr Pradeep Manuneedhi Cholan is a post-doctoral fellow at the Macquarie University, Australia. He earned his Doctor of Philosophy from University of Sydney in 2019. His field of interest include studying the role of gut microbiome in various pathological conditions using germ-free zebrafish models. He is currently researching the impact of motor neuron disease on the gut microbiome.
The article has been published in BioFactors, Volume 48, Issue 2, 2022.
|Yalda Rahbar Saadat|
“Glucocorticoid receptors and their upstream epigenetic regulators in adults with steroid-resistant nephrotic syndrome”
Yalda Rahbar Saadat has recently received her Ph.D. from Tabriz University of Medical Sciences (2021). Her primary research interests lie in the area of cancer, with particular emphasis on targeting vital signaling pathways employing probiotics, postbiotics and nutraceuticals. Pursuing her interest in molecular and cell biology, she is currently interested in the molecular basis of renal diseases in order to develop new therapeutic approaches. She is the author/coauthor of more than 30 papers in peer-reviewed international journals and more than 10 international/national conference contributions.
The article has been published in BioFactors, Volume 46, Issue 6, 2020.
“Resveratrol modulates epigenetic regulators of promoter histone methylation and acetylation that restores BRCA1, p53, p21CIP1 in human breast cancer cell lines”
Biji Chatterjee is a Postdoctoral fellow in the laboratory of Professor Sadhan Majumder at the Department of Genetics, The University of Texas MD Anderson Cancer Center in Houston, Texas, USA. She is currently engaged in studying the epigenetic and transcriptional mechanisms in chronic pain induced by nerve injury. Prior to this, she completed her Ph.D. in Biochemistry from the Central University of Kerala, Kasaragod, Kerala, India, where in the laboratory of Dr. Santosh R. Kanade, she explored the impact of various natural molecules on the epigenetic modulators known to be associated with oncogenesis. In her spare time, Biji enjoys exploring the piano notes!
The article has been published in BioFactors, Volume 45, Issue 5, 2020.
“Chondroitin sulfate inhibits secretion of TNF and CXCL8 from human mast cells stimulated by IL‐33”
Amanda Gross completed her PhD in Pharmacology & Experimental Therapeutics in 2018 at Tufts University in the laboratory of Dr. Theoharis Theoharides, where she studied the inhibitory effects of glycosaminoglycans on activated human mast cells. Prior to her PhD, she completed her B.S. in Biology at the University of Florida. Currently, she is a Scientist within the Genomic Immunology group at GlaxoSmithKline (GSK) in Cambridge, MA, where she is supporting target validation for autoimmune disease and immuno-oncology projects. In her spare time, Amanda enjoys playing ultimate frisbee and exploring new restaurants in town.
The article has been published in BioFactors, Volume 45, Issue 1, 2019.
“1,2,4-trihydroxynaphthalene-2-O-β-D-glucopyranoside delays amyloid-β42 aggregation and reduces amyloid cytotoxicity”
Zohra Dhouafli is a research fellow at the laboratory of aromatic and medicinal plants at the Center of Biotechnology, Ecopark of Borj Cédria, Tunisia. Recently, she received her PhD (2018) in biological sciences from the Faculty of Science of Tunis, Tunisia under the guidance of Dr El Akrem Hayouni and Pr Moufida Saidani Tounsi. During her doctoral research, she studied the effect of natural phenolic compounds on amyloid aggregation and their associated toxicity. Those investigations were conducted in collaboration with national (Laboratory of heterocyclic chemistry, Team: medicinal chemistry and natural products, Faculty of Science of Monastir and Laboratory of Chemistry, Chott Meriem Agronomical Institute, Sousse) and international laboratories from Italy (Department of Biomedical, Experimental and Clinical Sciences ‘Mario Serio’, University of Florence), France (Institute of Chemistry of Environments and Materials of Poitiers) and USA (Mitchell Center for Alzheimer’s Disease and Related Brain Disorders, University of Texas Medical School at Houston). She is currently interested in the production on a large scale (using Centrifuge Partition Chromatography and preparative chromatography) of bioactive molecules with a high inhibitory effect on amyloid aggregation. Furthermore, she is interested in exploring the effect of bioactive compounds extracted from Lawonia inermis on amyloid aggregation during Alzheimer disease in vivo.
The article has been published in BioFactors, Volume 44, Issue 3, 2018.