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EMBO | EMBL Symposium: DNA replication and genome maintenance: from basic biology to human health

Event category: EMBL

Date: October 20, 2026 to October 23, 2026

Event website: https://www.embl.org/about/info/course-and-conference-office/events/EES26-13/

Location: EMBL Heidelberg and Virtual, EMBL Advanced Training Centre

Organizers:

Anja Groth, University of Copenhagen, Denmark
Helle Ulrich, Institute of Molecular Biology (IMB), Germany
Johannes Walter, Harvard Medical School, USA

 

Event description

This conference will take place at EMBL Heidelberg, with the option to attend virtually.

 

Symposium overview

Our understanding of eukaryotic DNA replication has grown dramatically in the past few years, and many areas are poised for further breakthroughs. These include the structure and dynamics of the DNA replication machinery and how origin firing is controlled in space and time across different tissues, during aging and in disease. It is now clear that DNA replication is tightly integrated with chromatin dynamics, epigenome maintenance and chromosome organisation, and as such the field is expanding its scope.

Accurate DNA replication is important for genomic stability, and several human diseases, most notably cancer, are driven by DNA replication stress. Due to the rapid advances in understanding replication fork structure and function we are now on the brink of a new understanding of replication fork stability, protection and repair. These forthcoming insights will advance our understanding of cancer etiology and lay the foundation for new therapies. By bringing together experts in the basic biology of DNA replication and genome maintenance, this EMBO | EMBL Symposium aims to fuel progress in these important fields.

 

Session topics

  • Replisome structure and function
  • Replication in time and space
  • Chromatin replication and cell fate
  • Replication stress and genome stability
  • Replication-coupled DNA repair
  • Replication in development, aging, and cancer

#EESReplication

EMBL

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