
EMBL Conference | Gene regulation: one molecule at a time
July 15 to July 18
This conference will take place at EMBL Heidelberg, with the option to attend virtually.
Conference Overview
Gene expression is controlled by the dynamic action of dozens of macromolecular complexes that assemble on DNA to transcribe genes and translate mRNAs to proteins. Understanding of these mechanisms has historically been driven by biochemical and structural characterisation of the players, as well as probing their function through genetic deletions. The genomics revolution has provided us with a near- comprehensive picture of where these factors bind to regulate the genome and which transcripts are processed in various biological contexts.
A key limitation of the resulting models is that they are derived using data that are static by nature, unfaithfully representing the dynamics of these regulatory processes in vivo. The last few years has seen the independent emergence of microscopy and genomics technologies to monitor gene regulation processes with single molecule resolution. Recording the dynamic function of regulatory proteins on DNA and RNA now opens opportunities to understand key parameters of the process such as its kinetics, or how various activities are combined in vivo.
This meeting will bring together pioneers of the single molecule microscopy and single molecule genomics field, as well as theoretical biologists to catalyze the emergence of a new generation of mechanistic models of the regulation of genes across each steps of the central dogma.
Session topics
- RNA processing
- Translation
- Transcription and chromatin regulation
- Method development
- Theory
Deadlines
APR 8: Abstract Submission
JUN 3: Registration (On-site)
JUL 8: Registration (Virtual)
On-site Registration | Virtual Registration
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