Congratulations to Patricia Recio López, whose paper was selected for the 2023 Wiley-BioFactors Young Investigator Award. Patricia is a PhD Student at the Department of Molecular Medicine and Surgery Signal Transduction Group, Karolinska Institutet, Sweden.
“I started my motivation for science during my childhood. I debuted as type 1 diabetes patient very early in life and since then, I have been in very close contact with hospitals, medical care and science advances throughout my life.
For that reason, I studied biology and specialized in sanitary biology during my bachelor studies at Complutense University of Madrid. After that, I did my masters studies in biomedicine with a special focus in diabetes and obesity, at the same university.
I performed my master thesis at Biomedical Research Institute “Alberto Sols” in Madrid. In this project, entitled as “Effects of a dual glucacon-GLP1 receptor agonist in the activation of brown adipose tissue in obese mice”, I had the aim to understand the effects of this dual agonist in the reduction of body weight, as well as in the lipolytic and thermogenic pathways in the different fat depots of the obese mice.
Once I finalized my masters’ studies, I felt I had to go abroad to get further experience in the research field. I applied for an ERASMUS + Practices at Karolinska Institute and I spent a year being involved in different projects trying to understand the role of apolipoprotein CIII (apoCIII) in diabetes and obesity. After that, I decided to continue working in the lab of Per-Olof Berggren group, to develop my thesis project in which I study the role of apoCIII in the pathophysiology of diabetes mellitus.
In the article “Treatment of the metabolic syndrome by siRNA targeting apolipoprotein CIII”, we take advantage of the small-interference RNA (siRNA) technology to develop apoCIII targeting siRNAs as a new strategy to reduce the levels of the apolipoprotein and study the consequences in obese and diabetic mice.”
– Patricia Recio López